P2Y14R antagonist 4
P2Y14R antagonist 4 (Compound 25l) is an orally active P2Y14R antagonist (IC50: 5.6 nM) with superior binding affinity to P2Y14R over PPTN. P2Y14R antagonist 4 has anti-inflammatory activity and reduces LPS (HY-D1056)-induced proinflammatory cytokines (IL-1β, IL-6, and TNF-α) release.
For research use only. We do not sell to patients.
- CAS No.: 3081687-67-1
- Formula: C27H27F3N2O4S
- Molecular Weight:532.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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P2Y14 Receptor 5.6 nM (IC50) |
Chemical Information
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CAS No. 3081687-67-1
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Molecular Weight 532.57
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Formula C27H27F3N2O4S
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SMILES
OC(C1=CC(C2=CC=C(C3CCNCC3)C=C2)=CC(NS(CCC4=CC=C(C(F)(F)F)C=C4)(=O)=O)=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
P2Y14R antagonist 4 Related Classifications
HY-173407 Related Classifications
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