3081687-67-1
3081687-67-1
Chemical Structure
P2Y14R antagonist 4
- CAS No.: 3081687-67-1
- Formula:C27H27F3N2O4S
- Molecular Weight:532.57
SMILES: OC(C1=CC(C2=CC=C(C3CCNCC3)C=C2)=CC(NS(CCC4=CC=C(C(F)(F)F)C=C4)(=O)=O)=C1)=O
Biological Activity: P2Y14R antagonist 4 (Compound 25l) is an orally active P2Y14R antagonist (IC50: 5.6 nM) with superior binding affinity to P2Y14R over PPTN. P2Y14R antagonist 4 has anti-inflammatory activity and reduces LPS (HY-D1056)-induced proinflammatory cytokines (IL-1β, IL-6, and TNF-α) release[1].
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P2Y14R antagonist 4 | P2Y14R antagonist 4 (Compound 25l) is an orally active P2Y14R antagonist (IC50: 5.6 nM) with superior binding affinity to P2Y14R over PPTN. P2Y14R antagonist 4 has anti-inflammatory activity and reduces LPS (HY-D1056)-induced proinflammatory cytokines (IL-1β, IL-6, and TNF-α) release. | |||||||||||||||||||||
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