Y13g dihydrochloride
Based on 1 Customer Validation
Y13g dihydrochloride is the potent inhibitor of both AChE and IL-6. Interleukin-6 (IL-6) and acetylcholinesterase (AChE) are two important targets implicated in progression of Alzheimer's Disease (AD). Y13g dihydrochloride reverses the STZ (HY-13753)-induced memory deficit, and shows histopathology similarly as in normal animals.
For research use only. We do not sell to patients.
- Purity: 99.89%
- Formula: C16H26Cl2N2O4
- Molecular Weight:381.29
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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AChE |
IL-6 |
Chemical Information
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Appearance Solid
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Molecular Weight 381.29
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Formula C16H26Cl2N2O4
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Color Off-white to light yellow
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SMILES
COC1=CC(O)=C(C(OC)=C1)C(CCCN2CCNCC2)=O.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (327.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6227 mL | 13.1134 mL | 26.2268 mL | 65.5669 mL |
| 5 mM | 0.5245 mL | 2.6227 mL | 5.2454 mL | 13.1134 mL | |
| 10 mM | 0.2623 mL | 1.3113 mL | 2.6227 mL | 6.5567 mL | |
| 15 mM | 0.1748 mL | 0.8742 mL | 1.7485 mL | 4.3711 mL | |
| 20 mM | 0.1311 mL | 0.6557 mL | 1.3113 mL | 3.2783 mL | |
| 25 mM | 0.1049 mL | 0.5245 mL | 1.0491 mL | 2.6227 mL | |
| 30 mM | 0.0874 mL | 0.4371 mL | 0.8742 mL | 2.1856 mL | |
| 40 mM | 0.0656 mL | 0.3278 mL | 0.6557 mL | 1.6392 mL | |
| 50 mM | 0.0525 mL | 0.2623 mL | 0.5245 mL | 1.3113 mL | |
| 60 mM | 0.0437 mL | 0.2186 mL | 0.4371 mL | 1.0928 mL | |
| 80 mM | 0.0328 mL | 0.1639 mL | 0.3278 mL | 0.8196 mL | |
| 100 mM | 0.0262 mL | 0.1311 mL | 0.2623 mL | 0.6557 mL |
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