Y13g dihydrochloride

Cat. No.: HY-115910A Purity: 99.89%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Y13g dihydrochloride is the potent inhibitor of both AChE and IL-6. Interleukin-6 (IL-6) and acetylcholinesterase (AChE) are two important targets implicated in progression of Alzheimer's Disease (AD). Y13g dihydrochloride reverses the STZ-induced memory deficit, and shows histopathology similarly as in normal animals.

For research use only. We do not sell to patients.

Y13g dihydrochloride Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 750	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Y13g dihydrochloride:

Y13g Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

AChE

IL-6

Molecular Weight

381.29

Formula

C₁₆H₂₆Cl₂N₂O₄

Appearance

Solid

Color

Off-white to light yellow

SMILES

COC1=CC(O)=C(C(OC)=C1)C(CCCN2CCNCC2)=O.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (327.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6227 mL	13.1134 mL	26.2268 mL
5 mM	0.5245 mL	2.6227 mL	5.2454 mL
10 mM	0.2623 mL	1.3113 mL	2.6227 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.89%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (247 KB) HNMR (282 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Kaur S, et al. Design, molecular Docking, synthesis and evaluation of xanthoxylin hybrids as dual inhibitors of IL-6 and acetylcholinesterase for Alzheimer's disease. Bioorg Chem. 2022;121:105670. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6227 mL	13.1134 mL	26.2268 mL	65.5669 mL
	5 mM	0.5245 mL	2.6227 mL	5.2454 mL	13.1134 mL
	10 mM	0.2623 mL	1.3113 mL	2.6227 mL	6.5567 mL
	15 mM	0.1748 mL	0.8742 mL	1.7485 mL	4.3711 mL
	20 mM	0.1311 mL	0.6557 mL	1.3113 mL	3.2783 mL
	25 mM	0.1049 mL	0.5245 mL	1.0491 mL	2.6227 mL
	30 mM	0.0874 mL	0.4371 mL	0.8742 mL	2.1856 mL
	40 mM	0.0656 mL	0.3278 mL	0.6557 mL	1.6392 mL
	50 mM	0.0525 mL	0.2623 mL	0.5245 mL	1.3113 mL
	60 mM	0.0437 mL	0.2186 mL	0.4371 mL	1.0928 mL
	80 mM	0.0328 mL	0.1639 mL	0.3278 mL	0.8196 mL
	100 mM	0.0262 mL	0.1311 mL	0.2623 mL	0.6557 mL