6-Maleimidocapronic acid
Based on 1 Customer Validation
6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.67%
- CAS No.: 55750-53-3
- Formula: C10H13NO4
- Molecular Weight:211.21
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All PROTAC Linkers Isoforms
More
Biological Activity
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Alkyl-Chain |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 55750-53-3
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Appearance Solid
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Molecular Weight 211.21
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Formula C10H13NO4
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Color White to off-white
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SMILES
O=C(N1CCCCCC(O)=O)C=CC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 200 mg/mL (946.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7346 mL | 23.6731 mL | 47.3462 mL | 118.3656 mL |
| 5 mM | 0.9469 mL | 4.7346 mL | 9.4692 mL | 23.6731 mL | |
| 10 mM | 0.4735 mL | 2.3673 mL | 4.7346 mL | 11.8366 mL | |
| 15 mM | 0.3156 mL | 1.5782 mL | 3.1564 mL | 7.8910 mL | |
| 20 mM | 0.2367 mL | 1.1837 mL | 2.3673 mL | 5.9183 mL | |
| 25 mM | 0.1894 mL | 0.9469 mL | 1.8938 mL | 4.7346 mL | |
| 30 mM | 0.1578 mL | 0.7891 mL | 1.5782 mL | 3.9455 mL | |
| 40 mM | 0.1184 mL | 0.5918 mL | 1.1837 mL | 2.9591 mL | |
| 50 mM | 0.0947 mL | 0.4735 mL | 0.9469 mL | 2.3673 mL | |
| 60 mM | 0.0789 mL | 0.3946 mL | 0.7891 mL | 1.9728 mL | |
| 80 mM | 0.0592 mL | 0.2959 mL | 0.5918 mL | 1.4796 mL | |
| 100 mM | 0.0473 mL | 0.2367 mL | 0.4735 mL | 1.1837 mL |
6-Maleimidocapronic acid Related Classifications
HY-77959 Related Classifications
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