1. PROTAC
  2. PROTAC Linker
  3. 6-Maleimidocapronic acid

6-Maleimidocapronic acid 

Cat. No.: HY-77959 Purity: 99.95%
Handling Instructions

6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

6-Maleimidocapronic acid Chemical Structure

6-Maleimidocapronic acid Chemical Structure

CAS No. : 55750-53-3

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Estimated Time of Arrival: December 31
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Description

6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

211.21

Formula

C₁₀H₁₃NO₄

CAS No.

55750-53-3

SMILES

O=C(N1CCCCCC(O)=O)C=CC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (946.92 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7346 mL 23.6731 mL 47.3462 mL
5 mM 0.9469 mL 4.7346 mL 9.4692 mL
10 mM 0.4735 mL 2.3673 mL 4.7346 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

6-Maleimidocapronic acidPROTAC LinkerInhibitorinhibitorinhibit

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Product Name:
6-Maleimidocapronic acid
Cat. No.:
HY-77959
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