6-Maleimidocapronic acid
Based on 1 Customer Validation
6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.67%
- CAS No.: 55750-53-3
- Formula: C10H13NO4
- Molecular Weight:211.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTAC Linkers Isoforms
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Biological Activity
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Alkyl-Chain |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 55750-53-3
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Appearance Solid
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Molecular Weight 211.21
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Formula C10H13NO4
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Color White to off-white
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SMILES
O=C(N1CCCCCC(O)=O)C=CC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 200 mg/mL (946.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7346 mL | 23.6731 mL | 47.3462 mL | 118.3656 mL |
| 5 mM | 0.9469 mL | 4.7346 mL | 9.4692 mL | 23.6731 mL | |
| 10 mM | 0.4735 mL | 2.3673 mL | 4.7346 mL | 11.8366 mL | |
| 15 mM | 0.3156 mL | 1.5782 mL | 3.1564 mL | 7.8910 mL | |
| 20 mM | 0.2367 mL | 1.1837 mL | 2.3673 mL | 5.9183 mL | |
| 25 mM | 0.1894 mL | 0.9469 mL | 1.8938 mL | 4.7346 mL | |
| 30 mM | 0.1578 mL | 0.7891 mL | 1.5782 mL | 3.9455 mL | |
| 40 mM | 0.1184 mL | 0.5918 mL | 1.1837 mL | 2.9591 mL | |
| 50 mM | 0.0947 mL | 0.4735 mL | 0.9469 mL | 2.3673 mL | |
| 60 mM | 0.0789 mL | 0.3946 mL | 0.7891 mL | 1.9728 mL | |
| 80 mM | 0.0592 mL | 0.2959 mL | 0.5918 mL | 1.4796 mL | |
| 100 mM | 0.0473 mL | 0.2367 mL | 0.4735 mL | 1.1837 mL |