1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. SMCC

SMCC 

Cat. No.: HY-42360
Handling Instructions

SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.

For research use only. We do not sell to patients.

SMCC Chemical Structure

SMCC Chemical Structure

CAS No. : 64987-85-5

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Description

SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses[1].

In Vitro

SMCC or sulfo-SMCC can use to conjugate keyhole limpet hemocyanin (KLH) and ovalbumin (OVA). In the the conjugation system, 300 μl KLH or OVA (3 mg) and 30 μl SMCC or Sulfo-SMCC (the final concentration of 0.1 mM) are added in PBS with final volume of 3 ml[1].

In Vivo

Using the SMCC-conjugation method is able to induce potent immune responses to whole protein or peptide antigens by injection of antigen-coupled syngeneic splenic mononuclear cells in mice[1].

Molecular Weight

334.32

Formula

C₁₆H₁₈N₂O₆

CAS No.

64987-85-5

SMILES

O=C(C1CCC(CN2C(C=CC2=O)=O)CC1)ON3C(CCC3=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Keywords:

SMCCADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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SMCC
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