6′-Methyl paeonol
6’-Methyl paeonol is a paeonol derivative, which inihibits abnormal depolarizations and reduces the Amyloid β-induced ERK phosphorylation. 6’-Methyl paeonol exhibits alleviating activity against Alzheimer’s Disease.
For research use only. We do not sell to patients.
- CAS No.: 6540-66-5
- Formula: C10H12O3
- Molecular Weight:180.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
6’-Methyl paeonol (0.1-100 μM) inhibits the NMDA- and AMPA-induced neuronal depolarization, and thereby ameliorates the Aβ-induced abnormal depolarization.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:C2C12
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Concentration:100 μM
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Incubation Time:2 h
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Result:Reversed the increase of ERK phosphorylation induced by Aβ
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:APP transgenic C57BL/6 mice (J20 mice)[1]
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Dosage:20 mg/kg
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Administration:subcutaneous injection
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Result:Reduced the time for mice reaching hidden platform.
Chemical Information
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CAS No. 6540-66-5
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Molecular Weight 180.20
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Formula C10H12O3
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SMILES
O=C(C)C1=C(C)C=C(OC)C=C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6′-Methyl paeonol Related Classifications
HY-163283 Related Classifications
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