Pedaliin 6''-acetate
Pedaliin 6''-acetate (compound 10) is a natural product that can be isolated from Dracocephalum tanguticum. Pedaliin 6''-acetate shows antioxidative activity and cytoprotective effect on doxorubicin (DOX)-induced toxicity in H9c2 cardiomyocytes with an EC50 value of 19.1 μM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 160789-41-3
- Formel: C24H24O13
- Molecular Weight:520.44
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| H9c2 | EC50 |
19.1 μM
Compound: 10
|
Cytoprotective activity against doxorubicin-induced cytotoxicity in rat H9c2 cells assessed as cell viability after 24 hrs by MTT assay
Cytoprotective activity against doxorubicin-induced cytotoxicity in rat H9c2 cells assessed as cell viability after 24 hrs by MTT assay
|
[PMID: 20932762] |
In Vitro
Pedaliin 6''-acetate scavenges 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical with an EC50 value of 95.24 μM[1]. Pedaliin 6''-acetate chelates ferrous ions with an EC50 value of 1.13 mM[1]. Pedaliin 6''-acetate scavenges ABTS+ cation radical with an EC50 value of 76.19 μM[1]. Pedaliin 6''-acetate shows cytoprotective effect on DOX-induced toxicity in H9c2 cardiomyocytes with an EC50 value of 19.1μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
CAS. Nr. 160789-41-3
-
Molecular Weight 520.44
-
Formel C24H24O13
-
SMILES
OC1=C2C(OC(C3=CC(O)=C(C=C3)O)=CC2=O)=CC(OC)=C1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)COC(C)=O
-
Structure Classification
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)