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Cat. No.: HY-N10642

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Pedaliin 6''-acetate

Pedaliin 6''-acetate (compound 10) is a natural product that can be isolated from Dracocephalum tanguticum. Pedaliin 6''-acetate shows antioxidative activity and cytoprotective effect on doxorubicin (DOX)-induced toxicity in H9c2 cardiomyocytes with an EC₅₀ value of 19.1 μM.

For research use only. We do not sell to patients.

CAS No.: 160789-41-3
Formula: C₂₄H₂₄O₁₃
Molecular Weight:520.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Pedaliin 6''-acetate Chemical Structure

CAS No.: 160789-41-3

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Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
H9c2	EC₅₀	19.1 μM Compound: 10	Cytoprotective activity against doxorubicin-induced cytotoxicity in rat H9c2 cells assessed as cell viability after 24 hrs by MTT assay Cytoprotective activity against doxorubicin-induced cytotoxicity in rat H9c2 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 20932762]

In Vitro

Pedaliin 6''-acetate scavenges 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical with an EC₅₀ value of 95.24 μM^[1].
Pedaliin 6''-acetate chelates ferrous ions with an EC₅₀ value of 1.13 mM^[1].
Pedaliin 6''-acetate scavenges ABTS⁺ cation radical with an EC₅₀ value of 76.19 μM^[1].
Pedaliin 6''-acetate shows cytoprotective effect on DOX-induced toxicity in H9c2 cardiomyocytes with an EC₅₀ value of 19.1μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 160789-41-3
Molecular Weight 520.44
Formula C₂₄H₂₄O₁₃
SMILES

OC1=C2C(OC(C3=CC(O)=C(C=C3)O)=CC2=O)=CC(OC)=C1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)COC(C)=O
Structure Classification
- Flavonoids
- Flavones
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang SQ, et al. Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6411-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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