1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 6-Phosphogluconic acid

6-Phosphogluconic acid 

Cat. No.: HY-113514
Handling Instructions

6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite.

For research use only. We do not sell to patients.

6-Phosphogluconic acid Chemical Structure

6-Phosphogluconic acid Chemical Structure

CAS No. : 921-62-0

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Description

6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite[1][2].

IC50 & Target[1][2]

Human Endogenous Metabolite

 

In Vitro

6-Phosphogluconic acid (0.5-2.0 mM) completely inhibits the activity of PGI with glucose 6-phosphate (0.05- 0.5 mM) as the substrate[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

276.14

Formula

C6H13O10P

CAS No.
SMILES

OC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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6-Phosphogluconic acid Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
6-Phosphogluconic acid
Cat. No.:
HY-113514
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