6-Phosphogluconic acid (trisodium)
Based on 1 Customer Validation
6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.96%
- CAS 番号: 53411-70-4
- 分子式: C6H10Na3O10P
- 分子量:342.08
-
保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
Metabolism/Protease Compound Library
HY-L012
-
Natural Product Library
HY-L021
-
Covalent Screening Library
HY-L036
-
Glucose Metabolism Compound Library
HY-L092
-
Human Metabolite Library
HY-L123
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Covalent Screening Library Plus
HY-L036P
-
Natural Product Library Plus
HY-L021P
-
Natural Product and Natural Product-Like Compound Library
HY-L021M
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
High-Throughput Natural Product Library
HY-L206
-
Mass Spectrometry Human Metabolite Library
HY-L215
-
Natural Product Diversity Scaffold Library
HY-L245
-
Lactic Acid Metabolite Compound Library
HY-L250
-
Mass Spectrometry Natural Product Library
HY-L262
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
More
生物活性
phosphoglucose isomerase[1]
6-Phosphogluconic acid trisodium (0.5-2.0 mM) completely inhibits the activity of PGI with glucose 6-phosphate (0.05- 0.5 mM) as the substrate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 53411-70-4
-
性状 Solid
-
分子量 342.08
-
分子式 C6H10Na3O10P
-
Color White to off-white
-
SMILES
O=C(O[Na])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(O[Na])(O[Na])=O
-
別名
6-ホスホグルコン酸 三ナトリウム塩
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
H2O : 116.67 mg/mL (341.06 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (273 KB)
-
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Gaitonde MK, et al. Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J Neurochem. 1989 May;52(5):1348-52. [Content Brief]
[2]. Hitosugi T, et al. Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell. 2012 Nov 13;22(5):585-600. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.9233 mL | 14.6165 mL | 29.2329 mL | 73.0823 mL |
| 5 mM | 0.5847 mL | 2.9233 mL | 5.8466 mL | 14.6165 mL | |
| 10 mM | 0.2923 mL | 1.4616 mL | 2.9233 mL | 7.3082 mL | |
| 15 mM | 0.1949 mL | 0.9744 mL | 1.9489 mL | 4.8722 mL | |
| 20 mM | 0.1462 mL | 0.7308 mL | 1.4616 mL | 3.6541 mL | |
| 25 mM | 0.1169 mL | 0.5847 mL | 1.1693 mL | 2.9233 mL | |
| 30 mM | 0.0974 mL | 0.4872 mL | 0.9744 mL | 2.4361 mL | |
| 40 mM | 0.0731 mL | 0.3654 mL | 0.7308 mL | 1.8271 mL | |
| 50 mM | 0.0585 mL | 0.2923 mL | 0.5847 mL | 1.4616 mL | |
| 60 mM | 0.0487 mL | 0.2436 mL | 0.4872 mL | 1.2180 mL | |
| 80 mM | 0.0365 mL | 0.1827 mL | 0.3654 mL | 0.9135 mL | |
| 100 mM | 0.0292 mL | 0.1462 mL | 0.2923 mL | 0.7308 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
6-Phosphogluconic acid trisodium 関連分類
HY-W011184 関連分類
Powered by Bioz