53411-70-4
53411-70-4
Chemical Structure
6-Phosphogluconic acid trisodium
- CAS No.: 53411-70-4
- Formula:C6H10Na3O10P
- Molecular Weight:342.08
IUPAC Name: sodium (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonatooxy)hexanoate
InChIKey: CBQSOSFCUWVWAQ-CXKLNRRHSA-K
SMILES: O=C(O[Na])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(O[Na])(O[Na])=O
Biological Activity: 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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6-Phosphogluconic acid trisodium | 99.96% | 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite. | ||||||||||||||||||||
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6-Phosphogluconic acid trisodium (Standard) | 86.39% | 6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-128374D-Glucose 6-phosphate disodium salt -
Similarity Score 0.83
HY-W854355D-Mannose-6-phosphate disodium -
Similarity Score 0.80
HY-113407AD-Fructose-6-phosphate disodium -
Similarity Score 0.80
HY-113407BD-Fructose-6-phosphate disodium hydrate -
Similarity Score 0.78
HY-167291D-Arabinose 5-phosphate sodium -
Similarity Score 0.78
HY-W009371RD-Ribose 5-phosphate disodium (Standard) -
Similarity Score 0.78
HY-W009371CD-Ribose 5-phosphate disodium dihydrate -
Similarity Score 0.77
HY-139409A2-Deoxy-D-glucose 6-phosphate disodium -
Similarity Score 0.77
HY-106950ARFosfructose trisodium (Standard) -
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References
- [1]. Gaitonde MK, et al. Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J Neurochem. 1989 May;52(5):1348-52. [Content Brief]
- [2]. Hitosugi T, et al. Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell. 2012 Nov 13;22(5):585-600. [Content Brief]
