6-O-Methyl-guanine
Based on 1 Customer Validation
6-O-Methyl-guanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 20535-83-5
- 分子式: C6H7N5O
- 分子量:165.16
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-HSB-2 | CC50 |
>20 μM
Compound: AMP
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Cytotoxicity against human HSB2 cells after 7 days by Cell-Titer Glo assay
Cytotoxicity against human HSB2 cells after 7 days by Cell-Titer Glo assay
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[PMID: 22607883] |
| HFF | CC50 |
171 μM
Compound: AMP
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Cytotoxicity against human HFF cells after 3 to 8 days by crystal voilet staining
Cytotoxicity against human HFF cells after 3 to 8 days by crystal voilet staining
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[PMID: 22607883] |
| HFF | IC50 |
>300 μM
Compound: AMP
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Antiviral activity against HSV-1 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
Antiviral activity against HSV-1 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
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[PMID: 22607883] |
| HFF | IC50 |
>300 μM
Compound: AMP
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Antiviral activity against HSV-2 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
Antiviral activity against HSV-2 infected in human HFF cells assessed as reduction in cytopathic effect after 3 days by crystal violet staining
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[PMID: 22607883] |
| HFF | IC50 |
2.8 μM
Compound: AMP
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Antiviral activity against HCMV infected in human HFF cells assessed as reduction in cytopathic effect after 8 days by plaque reduction assay
Antiviral activity against HCMV infected in human HFF cells assessed as reduction in cytopathic effect after 8 days by plaque reduction assay
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[PMID: 22607883] |
| HFF | IC50 |
7.4 μM
Compound: AMP
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Antiviral activity against VZV infected in human HFF cells assessed as reduction in cytopathic effect after 7 days by crystal violet staining
Antiviral activity against VZV infected in human HFF cells assessed as reduction in cytopathic effect after 7 days by crystal violet staining
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[PMID: 22607883] |
| HT-29 | ED50 |
120 μM
Compound: 7
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Inhibitory activity against alkyl transferase in HT-29 cells
Inhibitory activity against alkyl transferase in HT-29 cells
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[PMID: 1447749] |
| HT-29 | ED50 |
350 μM
Compound: 7
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In vitro inhibition of human alkyl transferase in HT-29 cell-free extracts.
In vitro inhibition of human alkyl transferase in HT-29 cell-free extracts.
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[PMID: 1447749] |
| HT-29 | IC50 |
248 μM
Compound: 1
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concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells
concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells
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[PMID: 11063604] |
| HT-29 | IC50 |
428 μM
Compound: 1
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Inhibition of AGT activity to 50% of control rate in HT-29 cell extract
Inhibition of AGT activity to 50% of control rate in HT-29 cell extract
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[PMID: 11063604] |
| MOLT-3 | CC50 |
>20 μM
Compound: AMP
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Cytotoxicity against human MOLT3 cells after 7 days by Cell-Titer Glo assay
Cytotoxicity against human MOLT3 cells after 7 days by Cell-Titer Glo assay
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[PMID: 22607883] |
| MOLT-3 | IC50 |
>20 μM
Compound: AMP
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Antiviral activity against HHV-6B infected in human Molt3 cells assessed as reduction in viral DNA after 7 days by hybridization assay
Antiviral activity against HHV-6B infected in human Molt3 cells assessed as reduction in viral DNA after 7 days by hybridization assay
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[PMID: 22607883] |
化学情報
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CAS 番号 20535-83-5
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性状 Solid
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分子量 165.16
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分子式 C6H7N5O
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Color White to off-white
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SMILES
NC1=NC(OC)=C2N=CNC2=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 20 mg/mL (121.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.0549 mL | 30.2744 mL | 60.5488 mL | 151.3720 mL |
| 5 mM | 1.2110 mL | 6.0549 mL | 12.1098 mL | 30.2744 mL | |
| 10 mM | 0.6055 mL | 3.0274 mL | 6.0549 mL | 15.1372 mL | |
| 15 mM | 0.4037 mL | 2.0183 mL | 4.0366 mL | 10.0915 mL | |
| 20 mM | 0.3027 mL | 1.5137 mL | 3.0274 mL | 7.5686 mL | |
| 25 mM | 0.2422 mL | 1.2110 mL | 2.4220 mL | 6.0549 mL | |
| 30 mM | 0.2018 mL | 1.0091 mL | 2.0183 mL | 5.0457 mL | |
| 40 mM | 0.1514 mL | 0.7569 mL | 1.5137 mL | 3.7843 mL | |
| 50 mM | 0.1211 mL | 0.6055 mL | 1.2110 mL | 3.0274 mL | |
| 60 mM | 0.1009 mL | 0.5046 mL | 1.0091 mL | 2.5229 mL | |
| 80 mM | 0.0757 mL | 0.3784 mL | 0.7569 mL | 1.8922 mL | |
| 100 mM | 0.0605 mL | 0.3027 mL | 0.6055 mL | 1.5137 mL |
6-O-Methyl-guanine 関連分類
HY-W013591 関連分類
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