1. Apoptosis
    Immunology/Inflammation
  2. TNF Receptor
    Interleukin Related
  3. Isoforskolin

Isoforskolin (Synonyms: Coleonol B)

Cat. No.: HY-N6927
Handling Instructions

Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis.

For research use only. We do not sell to patients.

Isoforskolin Chemical Structure

Isoforskolin Chemical Structure

CAS No. : 64657-21-2

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Description

Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].

In Vitro

Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA)[1].

Molecular Weight

410.50

Formula

C₂₂H₃₄O₇

CAS No.

64657-21-2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

IsoforskolinColeonol BTNF ReceptorInterleukin RelatedTumor Necrosis Factor ReceptorTNFRILTNF-αIL-1βIL-6 and IL-8LymearthritisInhibitorinhibitorinhibit

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