sEH inhibitor-19
sEH inhibitor-19 (Compound (R)-14i) is an orally active inhibitor for soluble epoxide hydrolase (sEH) with an IC50 of 1.2 nM. sEH inhibitor-19 inhibits the expression of TNF-α and IL-6, exhibits anti-inflammatory activity in mouse acute pancreatitis or Carrageenan (HY-125474)-induced edema models.
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- CAS. Nr.: 3107483-12-2
- Formel: C28H28F3N3O4
- Molecular Weight:527.53
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 3107483-12-2
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Molecular Weight 527.53
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Formel C28H28F3N3O4
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SMILES
O=C(NCC1=CC=C(OC(F)(F)F)C=C1)NC2=CC(C3)=C(C=C2)C[C@@]4([H])N3CCC5=C4C=C(OC)C(OC)=C5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
sEH inhibitor-19 Related Classifications
HY-170492 Related Classifications
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