Talaroterphenyl A
Talaroterphenyl A (compound 1) is a p-terphenyl derivative present in the mangrove sediment-derived fungus Talaromyces sp. SCSIO 41412, which exhibits phosphodiesterase 4 (PDE4) inhibitory activity (IC50=1.2 μM). Talaroterphenyl A also exhibits anti-inflammatory and anti-fibrotic activities, significantly reducing the mRNA levels of pro-inflammatory cytokines IL-6, TNF-α, and IL-1β.
For research use only. We do not sell to patients.
- Formula: C22H20O5
- Molecular Weight:364.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PDE4 1.2 μM (IC50) |
Chemical Information
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Molecular Weight 364.39
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Formula C22H20O5
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SMILES
OC1=C(C2=CC=CC=C2)C(OC(C)=O)=C(OC)C(C3=CC=CC=C3)=C1OC
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Structure Classification
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Initial Source
Marine-Derived Fungi
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)