IL-17-IN-1
Based on 1 publication(s) in Google Scholar
IL-17-IN-1 (26) is an orally active IL-17 inhibitor, with IC50 values of 0.013 μM and 0.004 μM for IL-17A and IL-6 release, respectively. IL-17-IN-1 (26) effectively reduces knee swelling in a rat arthritis model.
For research use only. We do not sell to patients.
- Formula: C26H30F6N6O3
- Molecular Weight:588.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) IL-17-IN-1
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Biological Activity
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Cell Line
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Type | Value | Description | References |
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| NHDF | IC50 |
0.004 μM
Compound: 26
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Inhibition of IL-6 production in IL-17/TNF-alpha stimulated human NHDF cells incubated for 24 hrs by ELISA
Inhibition of IL-6 production in IL-17/TNF-alpha stimulated human NHDF cells incubated for 24 hrs by ELISA
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[PMID: 39276085] |
Chemical Information
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Molecular Weight 588.55
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Formula C26H30F6N6O3
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SMILES
O=C1N[C@H](C(F)(F)F)CN1[C@H](COC)C2=CC3=NC([C@H](C4CCC(F)(CC4)F)NC(/C(F)=C\C5CC5)=O)=CN3N=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
Injectable hydrogel regulates immune infiltration through physical and chemical synergy in the treatment of steroid-induced osteonecrosis of the femoral head. [Abstract]2025 Jan 21:31:101511. PMID: 39925717
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IL-17-IN-1 Related Classifications
HY-168084 Related Classifications
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