Taurohyodeoxycholic acid sodium
Based on 2 publication(s) in Google Scholar
Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 38411-85-7
- Formula: C26H44NNaO6S
- Molecular Weight:521.69
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Taurohyodeoxycholic acid sodium
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Biological Activity
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IL-6 |
TNFR1 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 38411-85-7
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Appearance Solid
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Molecular Weight 521.69
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Formula C26H44NNaO6S
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Color White to off-white
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SMILES
C[C@@]12[C@]3([H])[C@](C[C@@H]([C@]1([H])C[C@@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Host Microbe
2025 Aug 19:S1931-3128(25)00291-4. PMID: 40848719 -
Phytomedicine
Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis. [Abstract]2023 Sep:118:154971. PMID: 37494875
Solvent & Solubility
H2O : 62.5 mg/mL (119.80 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Roda A, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5. [Content Brief]
[2]. Angelico M, et al. Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHs. Scand J Gastroenterol. 1995 Dec;30(12):1178-85. [Content Brief]
[3]. Angelico M, et al. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat. Dig Dis Sci. 1994 Nov;39(11):2389-97. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.9168 mL | 9.5842 mL | 19.1685 mL | 47.9212 mL |
| 5 mM | 0.3834 mL | 1.9168 mL | 3.8337 mL | 9.5842 mL | |
| 10 mM | 0.1917 mL | 0.9584 mL | 1.9168 mL | 4.7921 mL | |
| 15 mM | 0.1278 mL | 0.6389 mL | 1.2779 mL | 3.1947 mL | |
| 20 mM | 0.0958 mL | 0.4792 mL | 0.9584 mL | 2.3961 mL | |
| 25 mM | 0.0767 mL | 0.3834 mL | 0.7667 mL | 1.9168 mL | |
| 30 mM | 0.0639 mL | 0.3195 mL | 0.6389 mL | 1.5974 mL | |
| 40 mM | 0.0479 mL | 0.2396 mL | 0.4792 mL | 1.1980 mL | |
| 50 mM | 0.0383 mL | 0.1917 mL | 0.3834 mL | 0.9584 mL | |
| 60 mM | 0.0319 mL | 0.1597 mL | 0.3195 mL | 0.7987 mL | |
| 80 mM | 0.0240 mL | 0.1198 mL | 0.2396 mL | 0.5990 mL | |
| 100 mM | 0.0192 mL | 0.0958 mL | 0.1917 mL | 0.4792 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Taurohyodeoxycholic acid sodium Related Classifications
HY-114360A Related Classifications
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