6-Methyluridine
Based on 1 Customer Validation
6-Methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents.
For research use only. We do not sell to patients.
- Purity: 99.02%
- CAS No.: 16710-13-7
- Formula: C10H14N2O6
- Molecular Weight:258.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
>1162 μM
Compound: 11
|
Cytotoxicity against CHO cells
Cytotoxicity against CHO cells
|
[PMID: 18189347] |
| COLO 205 | IC50 |
>50 μM
Compound: 18
|
Antitumor activity against human COLO205 cells after 3 days by WST1 assay
Antitumor activity against human COLO205 cells after 3 days by WST1 assay
|
[PMID: 19260677] |
| MCF7 | IC50 |
>50 μM
Compound: 18
|
Antitumor activity against human MCF7 cells after 3 days by WST1 assay
Antitumor activity against human MCF7 cells after 3 days by WST1 assay
|
[PMID: 19260677] |
| MDA-MB-468 | IC50 |
>50 μM
Compound: 18
|
Antitumor activity against human MDA468 cells after 3 days by WST1 assay
Antitumor activity against human MDA468 cells after 3 days by WST1 assay
|
[PMID: 19260677] |
| OCI-AML2 | IC50 |
>50 μM
Compound: 18
|
Antitumor activity against human OCI-AML2 cells after 3 days by WST1 assay
Antitumor activity against human OCI-AML2 cells after 3 days by WST1 assay
|
[PMID: 19260677] |
| OCI-Ly7 | IC50 |
>50 μM
Compound: 18
|
Antitumor activity against human OCI-LY7 cells after 3 days by WST1 assay
Antitumor activity against human OCI-LY7 cells after 3 days by WST1 assay
|
[PMID: 19260677] |
| OVCAR-4 | IC50 |
>50 μM
Compound: 18
|
Antitumor activity against human OVCAR4 cells after 3 days by WST1 assay
Antitumor activity against human OVCAR4 cells after 3 days by WST1 assay
|
[PMID: 19260677] |
Chemical Information
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CAS No. 16710-13-7
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Appearance Solid
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Molecular Weight 258.23
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Formula C10H14N2O6
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Color White to off-white
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C(C)=C2)C(NC2=O)=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (193.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8725 mL | 19.3626 mL | 38.7252 mL | 96.8129 mL |
| 5 mM | 0.7745 mL | 3.8725 mL | 7.7450 mL | 19.3626 mL | |
| 10 mM | 0.3873 mL | 1.9363 mL | 3.8725 mL | 9.6813 mL | |
| 15 mM | 0.2582 mL | 1.2908 mL | 2.5817 mL | 6.4542 mL | |
| 20 mM | 0.1936 mL | 0.9681 mL | 1.9363 mL | 4.8406 mL | |
| 25 mM | 0.1549 mL | 0.7745 mL | 1.5490 mL | 3.8725 mL | |
| 30 mM | 0.1291 mL | 0.6454 mL | 1.2908 mL | 3.2271 mL | |
| 40 mM | 0.0968 mL | 0.4841 mL | 0.9681 mL | 2.4203 mL | |
| 50 mM | 0.0775 mL | 0.3873 mL | 0.7745 mL | 1.9363 mL | |
| 60 mM | 0.0645 mL | 0.3227 mL | 0.6454 mL | 1.6135 mL | |
| 80 mM | 0.0484 mL | 0.2420 mL | 0.4841 mL | 1.2102 mL | |
| 100 mM | 0.0387 mL | 0.1936 mL | 0.3873 mL | 0.9681 mL |