Mcl-1-IN-20
Mcl-1-IN-20 (Compound 26d) is a Mcl-1 inhibitor with Kis of 0.59, 6.6 and 3.6 μM against Mcl-1, Bcl-xL and Bcl-2. Mcl-1-IN-20 exhibits significant anti-proliferative activity against pancreatic cancer cells and can induce apoptosis in BxPC-3 cells. Mcl-1-IN-20 can be used for the study of pancreatic cancer.
For research use only. We do not sell to patients.
- Formula: C35H29ClN4O6S2
- Molecular Weight:701.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Mcl-1 0.59 μM (Ki) |
Bcl-xL 6.6 μM (Ki) |
Bcl-2 3.6 μM (Ki) |
Chemical Information
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Molecular Weight 701.21
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Formula C35H29ClN4O6S2
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SMILES
O=C(NS(=O)(C1=CC=C(Cl)C([N+]([O-])=O)=C1)=O)CN2C(SCCOC3=C4C=CC=CC4=CC=C3)=NC5=CC=CC(C6=CC=C(CC)C=C6)=C25
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mcl-1-IN-20 Related Classifications
HY-178910 Related Classifications
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