6,7-Dihydroxy-4-coumarinylacetic acid
Based on 1 Customer Validation
6,7-Dihydroxy-4-coumarinylacetic acid is a potent and selective inhibitor of ALR2. 6,7-Dihydroxy-4-coumarinylacetic acid inhibits ALR2, SDH andALR1 with IC50s of 9.6, 288 and 66.3 μM, respectively. 6,7-Dihydroxy-4-coumarinylacetic acid clearly suppresses galactitol accumulation.
For research use only. We do not sell to patients.
- Purity: 95.58%
- CAS No.: 88404-14-2
- Formula: C11H8O6
- Molecular Weight:236.18
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 88404-14-2
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Appearance Solid
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Molecular Weight 236.18
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Formula C11H8O6
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Color Light yellow to brown
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SMILES
O=C(O)CC(C1=CC(O)=C(O)C=C1O2)=CC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 25 mg/mL (105.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2341 mL | 21.1703 mL | 42.3406 mL | 105.8515 mL |
| 5 mM | 0.8468 mL | 4.2341 mL | 8.4681 mL | 21.1703 mL | |
| 10 mM | 0.4234 mL | 2.1170 mL | 4.2341 mL | 10.5851 mL | |
| 15 mM | 0.2823 mL | 1.4114 mL | 2.8227 mL | 7.0568 mL | |
| 20 mM | 0.2117 mL | 1.0585 mL | 2.1170 mL | 5.2926 mL | |
| 25 mM | 0.1694 mL | 0.8468 mL | 1.6936 mL | 4.2341 mL | |
| 30 mM | 0.1411 mL | 0.7057 mL | 1.4114 mL | 3.5284 mL | |
| 40 mM | 0.1059 mL | 0.5293 mL | 1.0585 mL | 2.6463 mL | |
| 50 mM | 0.0847 mL | 0.4234 mL | 0.8468 mL | 2.1170 mL | |
| 60 mM | 0.0706 mL | 0.3528 mL | 0.7057 mL | 1.7642 mL | |
| 80 mM | 0.0529 mL | 0.2646 mL | 0.5293 mL | 1.3231 mL | |
| 100 mM | 0.0423 mL | 0.2117 mL | 0.4234 mL | 1.0585 mL |