VEGFR-2-IN-69
VEGFR-2-IN-69 (Compound 5A) is a dual inhibitor of VEGFR-2 and Telomerase, which upregulates the expression of caspase 3, caspase 8 and caspase 9, while downregulating CDK-2, CDK-4 and CDK-6. VEGFR-2-IN-69 exhibits an IC50 of 15.46 µM against HCT116 cells.
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- Fòrmula: C18H16ClN5O
- Peso molecular:353.81
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Caspase
MoreVer todos los productos específicos de isoformas VEGFR
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Actividad biológica
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CDK2 |
CDK4 |
CDK6 |
Caspase 8 |
Caspase 3 |
Caspase 9 |
Chemical Information
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Peso molecular 353.81
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Fòrmula C18H16ClN5O
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SMILES
CC1=C(N=NN1C2=CC=C(C=C2)Cl)C(N/N=C(C3=CC=CC=C3)\C)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)