2. Cell Cycle/DNA Damage Anti-infection
  3. Nucleoside Antimetabolite/Analog Bacterial
  4. Chloropurine riboside

Chloropurine riboside  (Synonyms: 6-Chloropurine riboside)

Cat. No.: HY-W007791 Purity: 99.93%
COA
SDS
Handling Instructions Technical Support

Chloropurine (6-Chloropurine) riboside is an analog of Adenosine (HY-B0228). Chloropurine riboside acts as a chemical modifier for affinity labeling of RNase A. Chloropurine riboside exhibits antibacterial activity and can be used in studies related to citrus Huanglongbing (HLB).

For research use only. We do not sell to patients.

Chloropurine riboside

Chloropurine riboside Chemical Structure

CAS No. : 5399-87-1

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Based on 1 publication(s) in Google Scholar

Chloropurine riboside Related Antibodies

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Description

Chloropurine (6-Chloropurine) riboside is an analog of Adenosine (HY-B0228). Chloropurine riboside acts as a chemical modifier for affinity labeling of RNase A. Chloropurine riboside exhibits antibacterial activity and can be used in studies related to citrus Huanglongbing (HLB)[1][2].

Cellular Effect
Cell Line Type Value Description References
Huh-7 CC50
> 200 μM
Compound: 7
Cytotoxicity against Huh7 cells by XTT assay
Cytotoxicity against Huh7 cells by XTT assay
[PMID: 17766124]
Huh-7 EC50
31 μM
Compound: 7
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
[PMID: 17766124]
Vero CC50
279 μM
Compound: 1
Cytotoxicity against Vero E6 cells
Cytotoxicity against Vero E6 cells
[PMID: 17336519]
Vero IC50
48.7 μM
Compound: 1
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
[PMID: 17336519]
In Vivo

Chloropurine riboside (500 mg/L; topical application; single administration) exhibits anti-citrus Huanglongbing (HLB) activity in naturally infected citrus leaves[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: field-collected from Longping Town, Luodian County, Guizhou Province, China[2]
Dosage: 500 mg/L
Administration: topical brushing; single administration
Result: Achieved an average anti-HLB inhibitory activity of 17.95% across 45 replicate tests.
Showed group average activities of 17.83%, 17.29%, 18.63%, 16.74%, and 19.26% with no significant differences between groups.
Covered individual replicate activity values ranging from 0.24% to 45.35%.
Molecular Weight

286.68

Formula

C10H11ClN4O4
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 99.93%

SDS (393 KB)

COA (256 KB) HNMR (122 KB) RP-HPLC (250 KB)

Handling Instructions (2659 KB)
References
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Chloropurine riboside Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chloropurine riboside5399-87-16-Chloropurine ribosideNucleoside Antimetabolite/AnalogBacterialRNase Acitrus huanglongbingHLBbovine pancreatic RNase ALys-91Lys-41Lys-37half-leaf methodCandidatus Liberibacter asiaticusLys-1Inhibitorinhibitorinhibit

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