Chloropurine riboside
Based on 1 Customer Validation
Chloropurine (6-Chloropurine) riboside is an analog of Adenosine (HY-B0228). Chloropurine riboside acts as a chemical modifier for affinity labeling of RNase A. Chloropurine riboside exhibits antibacterial activity and can be used in studies related to citrus Huanglongbing (HLB).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.12%
- CAS 番号: 5399-87-1
- 分子式: C10H11ClN4O4
- 分子量:286.68
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>200 μM
Compound: 7
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Cytotoxicity against Huh7 cells by XTT assay
Cytotoxicity against Huh7 cells by XTT assay
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[PMID: 17766124] |
| Huh-7 | EC50 |
31 μM
Compound: 7
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Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
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[PMID: 17766124] |
| Vero | CC50 |
279 μM
Compound: 1
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Cytotoxicity against Vero E6 cells
Cytotoxicity against Vero E6 cells
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[PMID: 17336519] |
| Vero | IC50 |
48.7 μM
Compound: 1
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Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
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[PMID: 17336519] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:field-collected from Longping Town, Luodian County, Guizhou Province, China[2]
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Dosage:500 mg/L
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Administration:topical brushing; single administration
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Result:Achieved an average anti-HLB inhibitory activity of 17.95% across 45 replicate tests.
Showed group average activities of 17.83%, 17.29%, 18.63%, 16.74%, and 19.26% with no significant differences between groups.
Covered individual replicate activity values ranging from 0.24% to 45.35%.
化学情報
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CAS 番号 5399-87-1
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性状 Solid
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分子量 286.68
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分子式 C10H11ClN4O4
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Color Off-white to yellow
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SMILES
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3Cl
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別名
Chloropurine riboside; 6-クロロプリンリボシド
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Alonso J, et al. Modification of bovine pancreatic ribonuclease A with 6-chloropurine riboside. Arch Biochem Biophys. 1986;246(2):681-689. [Content Brief]
[2]. Luo X, et al. Screening Method and Antibacterial Activity of 1,3,4-Oxadiazole Sulfone Compounds against Citrus Huanglongbing. Int J Mol Sci. 2023;24(13):10515. Published 2023 Jun 22. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Chloropurine riboside 関連分類
HY-W007791 関連分類
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