Chloropurine riboside
Based on 1 Customer Validation
Chloropurine (6-Chloropurine) riboside is an analog of Adenosine (HY-B0228). Chloropurine riboside acts as a chemical modifier for affinity labeling of RNase A. Chloropurine riboside exhibits antibacterial activity and can be used in studies related to citrus Huanglongbing (HLB).
For research use only. We do not sell to patients.
- Purity: 98.12%
- CAS No.: 5399-87-1
- Formula: C10H11ClN4O4
- Molecular Weight:286.68
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>200 μM
Compound: 7
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Cytotoxicity against Huh7 cells by XTT assay
Cytotoxicity against Huh7 cells by XTT assay
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[PMID: 17766124] |
| Huh-7 | EC50 |
31 μM
Compound: 7
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Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
Inhibition of HCV replication in Huh7 cells after 48 hrs by luciferase assay
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[PMID: 17766124] |
| Vero | CC50 |
279 μM
Compound: 1
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Cytotoxicity against Vero E6 cells
Cytotoxicity against Vero E6 cells
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[PMID: 17336519] |
| Vero | IC50 |
48.7 μM
Compound: 1
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Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
Antiviral activity against SARS-CoV Frankfurt1 in Vero E6 cells by plaque reduction assay
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[PMID: 17336519] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:field-collected from Longping Town, Luodian County, Guizhou Province, China[2]
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Dosage:500 mg/L
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Administration:topical brushing; single administration
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Result:Achieved an average anti-HLB inhibitory activity of 17.95% across 45 replicate tests.
Showed group average activities of 17.83%, 17.29%, 18.63%, 16.74%, and 19.26% with no significant differences between groups.
Covered individual replicate activity values ranging from 0.24% to 45.35%.
Chemical Information
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CAS No. 5399-87-1
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Appearance Solid
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Molecular Weight 286.68
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Formula C10H11ClN4O4
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Color Off-white to yellow
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SMILES
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3Cl
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Synonyms
6-Chloropurine riboside
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Alonso J, et al. Modification of bovine pancreatic ribonuclease A with 6-chloropurine riboside. Arch Biochem Biophys. 1986;246(2):681-689. [Content Brief]
[2]. Luo X, et al. Screening Method and Antibacterial Activity of 1,3,4-Oxadiazole Sulfone Compounds against Citrus Huanglongbing. Int J Mol Sci. 2023;24(13):10515. Published 2023 Jun 22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chloropurine riboside Related Classifications
HY-W007791 Related Classifications
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