2-Amino-6-chloropurine
Based on 1 Customer Validation
6-Chloroguanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 10310-21-1
- Formula: C5H4ClN5
- Molecular Weight:169.57
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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CAS No. 10310-21-1
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Appearance Solid
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Molecular Weight 169.57
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Formula C5H4ClN5
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Color White to light yellow
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SMILES
NC1=NC(Cl)=C(NC=N2)C2=N1
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Synonyms
6-Chloropurines
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 31.82 mg/mL (187.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.8973 mL | 29.4863 mL | 58.9727 mL | 147.4317 mL |
| 5 mM | 1.1795 mL | 5.8973 mL | 11.7945 mL | 29.4863 mL | |
| 10 mM | 0.5897 mL | 2.9486 mL | 5.8973 mL | 14.7432 mL | |
| 15 mM | 0.3932 mL | 1.9658 mL | 3.9315 mL | 9.8288 mL | |
| 20 mM | 0.2949 mL | 1.4743 mL | 2.9486 mL | 7.3716 mL | |
| 25 mM | 0.2359 mL | 1.1795 mL | 2.3589 mL | 5.8973 mL | |
| 30 mM | 0.1966 mL | 0.9829 mL | 1.9658 mL | 4.9144 mL | |
| 40 mM | 0.1474 mL | 0.7372 mL | 1.4743 mL | 3.6858 mL | |
| 50 mM | 0.1179 mL | 0.5897 mL | 1.1795 mL | 2.9486 mL | |
| 60 mM | 0.0983 mL | 0.4914 mL | 0.9829 mL | 2.4572 mL | |
| 80 mM | 0.0737 mL | 0.3686 mL | 0.7372 mL | 1.8429 mL | |
| 100 mM | 0.0590 mL | 0.2949 mL | 0.5897 mL | 1.4743 mL |