PROTAC HDAC6 degrader 8
HDAC6 degrader-6 (Compound 11b) is a potent and selective HDAC6 PROTAC degrader with a DC50 of 1.9 nM. HDAC6 degrader-6 has no effect on the protein levels of other HDAC family members and does not degrade IKZF1, IKZF3, and GSPT1. HDAC6 degrader-6 can be used to study multiple myeloma.
(Pink: HDAC6 ligand (HY-177776); Blue: Cereblon ligand (HY-W998281); Black: linker).
For research use only. We do not sell to patients.
- Formula: C33H37N5O7
- Molecular Weight:615.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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HDAC6 1.9 nM (DC50) |
Cereblon |
Chemical Information
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Molecular Weight 615.68
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Formula C33H37N5O7
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SMILES
O=C(CCCCCCC(N/N=C/C1=CC=C(C=C1)OCCCC#CC2=CC=CC3=C2CN(C3=O)C(C(N4)=O)CCC4=O)=O)NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC HDAC6 degrader 8 Related Classifications
HY-177758 Related Classifications
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