1. GPCR/G Protein
  2. Protease-Activated Receptor (PAR)
  3. TRAP-6

TRAP-6 (Synonyms: PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6)

Cat. No.: HY-P0078 Purity: 99.84%
Handling Instructions

TRAP-6 is a protease-activated receptor 1 (PAR1) agonist.

For research use only. We do not sell to patients.

TRAP-6 Chemical Structure

TRAP-6 Chemical Structure

CAS No. : 141136-83-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 237 In-stock
Estimated Time of Arrival: December 31
5 mg USD 144 In-stock
Estimated Time of Arrival: December 31
10 mg USD 240 In-stock
Estimated Time of Arrival: December 31
25 mg USD 528 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products

Publications Citing Use of MCE TRAP-6

    TRAP-6 purchased from MCE. Usage Cited in: Mol Med Rep. 2019 Jun;19(6):5291-5300.

    Detection of expression levels of p‑AKT, AKT, p‑JNK, JNK and NF‑κB using western blotting. Groups: NC, negative control group; CH, a cholesterol stimulation group; CH+T, cholesterol stimulation with TRAP‑6 treatment group; CH+V, cholesterol stimulation with vorapaxar treatment group.
    • Biological Activity

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    Description

    TRAP-6 is a protease-activated receptor 1 (PAR1) agonist.

    Molecular Weight

    748.87

    Formula

    C₃₄H₅₆N₁₀O₉

    CAS No.

    141136-83-6

    Sequence

    Ser-Phe-Leu-Leu-Arg-Asn

    Sequence Shortening

    SFLLRN

    SMILES

    O=C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CCCNC(N)=N)C(N[[email protected]](C(O)=O)CC(N)=O)=O)=O)=O)[[email protected]@H](NC([[email protected]@H](N)CO)=O)CC1=CC=CC=C1

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -80°C 2 years
      -20°C 1 year
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    H2O : 33.33 mg/mL (44.51 mM; Need ultrasonic)

    DMSO : ≥ 28 mg/mL (37.39 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.3353 mL 6.6767 mL 13.3535 mL
    5 mM 0.2671 mL 1.3353 mL 2.6707 mL
    10 mM 0.1335 mL 0.6677 mL 1.3353 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
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    • Molarity Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
    C1   V1   C2   V2

    Keywords:

    TRAP-6PAR-1 agonist peptideThrombin Receptor Activator Peptide 6TRAP6TRAP 6Thrombin Receptor Activator Peptide6Thrombin Receptor Activator Peptide-6Protease-Activated Receptor (PAR)Thrombin receptorsInhibitorinhibitorinhibit

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    Product name:
    TRAP-6
    Cat. No.:
    HY-P0078
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