Nrf2 activator 18
Nrf2 activator 18 (Compound 11a) is an orally active activator for Keap1/Nrf2/HO-1 signaling pathway, that promotes the Nrf2 nuclear translocation, and enhances the antioxidant efficacy. Nrf2 activator 18 inhibits the release of IL-6 with an IC50 of 4.816 μM. Nrf2 activator 18 exhibits anti-inflammatory efficacy in mouse PM2.5-induced lung injury model.
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- Formule: C23H24FN3O
- Masse moléculaire:377.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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Masse moléculaire 377.45
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Formule C23H24FN3O
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SMILES
CN(C(C1=NN(C(C(C)(C)C)=C1)C2=CC=C(C=C2)F)=O)/C=C\C3=CC=CC=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nrf2 activator 18 Related Classifications
HY-168709 Related Classifications
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