2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease GPCR/G Protein
  3. Reactive Oxygen Species (ROS) Interleukin Related Prostaglandin Receptor
  4. (E/Z)-3-Hydroxylicochalcone A

(E/Z)-3-Hydroxylicochalcone A (Compound 1) is a flavonoid found in licorice (Glycyrrhiza inflata and
Glycyrrhiza uralensis), with antioxidant and anti-inflammatory activity. (E/Z)-3-Hydroxylicochalcone A inhibits lipid peroxidation in rat liver microsomes. (E/Z)-3-Hydroxylicochalcone A inhibits LPS (HY-D1056)-induced ROS, NO, IL-6, and PGE2 production.

For research use only. We do not sell to patients.

(E/Z)-3-Hydroxylicochalcone A

(E/Z)-3-Hydroxylicochalcone A Chemical Structure

CAS No. : 1083200-74-1

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(E/Z)-3-Hydroxylicochalcone A Related Antibodies

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Description

(E/Z)-3-Hydroxylicochalcone A (Compound 1) is a flavonoid found in licorice (Glycyrrhiza inflata and
Glycyrrhiza uralensis), with antioxidant and anti-inflammatory activity. (E/Z)-3-Hydroxylicochalcone A inhibits lipid peroxidation in rat liver microsomes. (E/Z)-3-Hydroxylicochalcone A inhibits LPS (HY-D1056)-induced ROS, NO, IL-6, and PGE2 production[1].

IC50 & Target[1]

IL-6

 

In Vitro

(E/Z)-3-Hydroxylicochalcone A (Compound DTM) inhibits lipid peroxidation in rat liver microsomes with an EC50 of 9.22 μM[1].
(E/Z)-3-Hydroxylicochalcone A (1-10 μM; 24 h) inhibits LPS (HY-D1056)-induced ROS production and NO, IL-6, and PGE2 levles in RAW 264.7 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(E/Z)-3-Hydroxylicochalcone A Related Antibodies
Molecular Weight

354.40

Formula

C21H22O5
CAS No.
SMILES

O=C(C1=CC=C(C=C1)O)/C=C/C2=C(OC)C(O)=C(O)C(C(C)(C)C=C)=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(E/Z)-3-Hydroxylicochalcone A Related Classifications

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Keywords:

(E/Z)-3-Hydroxylicochalcone A1083200-74-1Reactive Oxygen Species (ROS)Interleukin RelatedProstaglandin ReceptorILGlycyrrhiza inflataanti-inflammatory activityreactive oxygen speciesrat liver microsomesinterleukin-6macrophagesGlycyrrhiza uralensisantioxidant activitylipid peroxidationnitric oxideInhibitorinhibitorinhibit

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