1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor

WAY-100635 Maleate 

Cat. No.: HY-10349A Purity: >98.0%
Handling Instructions

WAY-100635 Maleate is a potent and selective 5-HT1A Receptor antagonist with a pIC50 of 8.87, an apparent pA2 of 9.71.

For research use only. We do not sell to patients.

WAY-100635 Maleate Chemical Structure

WAY-100635 Maleate Chemical Structure

CAS No. : 1092679-51-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 83 In-stock
Estimated Time of Arrival: December 31
5 mg USD 70 In-stock
Estimated Time of Arrival: December 31
10 mg USD 108 In-stock
Estimated Time of Arrival: December 31
50 mg USD 390 In-stock
Estimated Time of Arrival: December 31
100 mg USD 690 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of WAY-100635 Maleate:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

WAY-100635 Maleate is a potent and selective 5-HT1A Receptor antagonist with a pIC50 of 8.87, an apparent pA2 of 9.71.

IC50 & Target[1]

5-HT1A Receptor

8.87 (pIC50)

5-HT1A Receptor

9.71 (pA2)

In Vitro

WAY-100635 Maleate is a potent and, at high concentrations, an insurmountable antagonist of the 5-HT1A receptor agonist action of 5-carboxamidotryptamine, with an apparent pA2 value (at 0.3 nM) of 9.71. WAY-100635 displaces specific binding of the 5-HT1A radioligand, [3H]8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin), to rat hippocampal membranes with a plCIC50 of 8.87[1].

Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (464.13 mM)

H2O : 25 mg/mL (46.41 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8565 mL 9.2826 mL 18.5653 mL
5 mM 0.3713 mL 1.8565 mL 3.7131 mL
10 mM 0.1857 mL 0.9283 mL 1.8565 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

538.64

Formula

C₂₉H₃₈N₄O₆

CAS No.

1092679-51-0

SMILES

O=C(O)/C=C\C(O)=O.O=C(N(C1=NC=CC=C1)CCN2CCN(CC2)C3=CC=CC=C3OC)C4CCCCC4.[1:1]

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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× = ×
C1   V1   C2   V2

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Product Name:
WAY-100635 Maleate
Cat. No.:
HY-10349A
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WAY-100635 Maleate

Cat. No.: HY-10349A