(6R,7R)-Epoxy-1-oleanen-3-ol
(6R,7R)-Epoxy-1-oleanen-3-ol is a triterpenoid that can be found in Boswellia ovalifoliolata, exhibiting anti-inflammatory activity. (6R,7R)-Epoxy-1-oleanen-3-ol inhibits TNF-α, IL-6, IL-8, and NO production in LPS (HY-D1056)-activated murine neutrophils. (6R,7R)-Epoxy-1-oleanen-3-ol can be used for the research on inflammatory conditions.
For research use only. We do not sell to patients.
- CAS No.: 1609645-89-7
- Formula: C30H48O2
- Molecular Weight:440.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-6 |
IL-8 |
(6R,7R)-Epoxy-1-oleanen-3-ol (compound 2) (1 μM; 3 h) significantly inhibits intracellular TNF-α expression by 55.01% in LPS-activated murine neutrophils[1].
(6R,7R)-Epoxy-1-oleanen-3-ol (1 μM) significantly reduces intracellular IL-6 and IL-8 levels in LPS-activated murine neutrophils[1].
(6R,7R)-Epoxy-1-oleanen-3-ol (1 μM; 4-5 h) significantly inhibits extracellular NO production in LPS-activated murine neutrophils[1].
(6R,7R)-Epoxy-1-oleanen-3-ol (1-100 μM) shows no cytotoxicity in THP1, COLO-205, or A549 cells at 1 μM or 10 μM but inhibits growth by 77% (THP1) and 81% (A549) at 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:murine neutrophils
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Concentration:1 μM
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Incubation Time:4-5 h
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Result:Significantly inhibited extracellular NO production in murine neutrophils.
Reduced NO levels from 237.74 to 139.66 μmol/mL.
Chemical Information
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CAS No. 1609645-89-7
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Molecular Weight 440.70
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Formula C30H48O2
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SMILES
C[C@@]12[C@@]3([H])[C@]([C@]4([H])[C@@](C1=CC[C@@]5([H])[C@]2(CC[C@@]6([C@@]5([H])CC(C)(CC6)C)C)C)(CC[C@H](C4(C)C)O)C)([H])O3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(6R,7R)-Epoxy-1-oleanen-3-ol Related Classifications
HY-N17395 Related Classifications
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