Cyanidin 3,5-diglucoside chloride
Based on 1 Customer Validation
Cyanidin 3,5-diglucoside chloride is an anthocyanin. Cyanidin 3,5-diglucoside chloride inhibits inflammatory cytokines (IL-1α, IL-1β, and IL-6) expression and NO production. Cyanidin 3,5-diglucoside chloride inhibits the phosphorylation of STAT3, IκB, ERK, p38, and AKT. Cyanidin 3,5-diglucoside chloride inhibits high pressure-induced decrease in GLAST. Cyanidin 3,5-diglucoside chloride exerts anti-inflammatory and skin barrier modulating effects. Cyanidin 3,5-diglucoside chloride can be used in retinal research.
For research use only. We do not sell to patients.
- Purity: 99.44%
- CAS No.: 2611-67-8
- Formula: C27H31ClO16
- Molecular Weight:646.98
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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IL-1β |
IL-1α |
IL-6 |
STAT3 |
Cyanidin 3,5-diglucoside chloride (10-50 μM) can significantly increase the survival rate of rat retinal Müller cells induced by hyperbaric pressure, inhibit the decrease in the expression of glutamate-aspartate transporter (GLAST) mRNA and protein in these cells caused by hyperbaric pressure[1].
Cyanidin 3,5-diglucoside chloride (1-10 μg/mL; 0-24 h) exert anti-inflammatory and skin barrier regulatory effects in the TNF-α/IL-17A/IFN-γ-induced HaCaT psoriasis model[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HaCaT human keratinocytes
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Concentration:1 μg/mL, 5 μg/mL, 10 μg/mL
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Incubation Time:2 h
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Result:Concentration-dependently inhibited the phosphorylation of STAT3, IκB, ERK, p38, and AKT.
Chemical Information
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CAS No. 2611-67-8
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Appearance Solid
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Molecular Weight 646.98
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Formula C27H31ClO16
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Color Brown to black
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SMILES
O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC2=CC(O)=CC3=[O+]C(C4=CC=C(O)C(O)=C4)=C(O[C@H]5[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O5)C=C23.[Cl-]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 50 mg/mL (77.28 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 1.5456 mL | 7.7282 mL | 15.4564 mL | 38.6411 mL |
| 5 mM | 0.3091 mL | 1.5456 mL | 3.0913 mL | 7.7282 mL | |
| 10 mM | 0.1546 mL | 0.7728 mL | 1.5456 mL | 3.8641 mL | |
| 15 mM | 0.1030 mL | 0.5152 mL | 1.0304 mL | 2.5761 mL | |
| 20 mM | 0.0773 mL | 0.3864 mL | 0.7728 mL | 1.9321 mL | |
| 25 mM | 0.0618 mL | 0.3091 mL | 0.6183 mL | 1.5456 mL | |
| 30 mM | 0.0515 mL | 0.2576 mL | 0.5152 mL | 1.2880 mL | |
| 40 mM | 0.0386 mL | 0.1932 mL | 0.3864 mL | 0.9660 mL | |
| 50 mM | 0.0309 mL | 0.1546 mL | 0.3091 mL | 0.7728 mL | |
| 60 mM | 0.0258 mL | 0.1288 mL | 0.2576 mL | 0.6440 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Cyanidin 3,5-diglucoside chloride Related Classifications
HY-129138 Related Classifications
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