2. Signaling Pathways
  3. NF-κB
  4. IKK
  5. IKK-β Isoform

IKK-β

 

IKK-β Related Products (31):

Cat. No. Product Name Effect Purity
  • HY-16561
    Resveratrol
    		Inhibitor 99.94%
    Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.
  • HY-10074
    TPCA-1
    		Inhibitor 99.72%
    TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM.
  • HY-13687
    IKK 16
    		Inhibitor 98.57%
    IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively.
  • HY-10172
    IMD-0354
    		Inhibitor 99.51%
    IMD-0354 (IKK2 Inhibitor V) is a selective IKKβ inhibitor which inhibits NF-κB activity.
  • HY-15473
    MLN120B
    		Inhibitor 99.94%
    MLN120B (ML120B) is a potent, ATP competitive, and orally active inhibitor of IKKβ with an IC50 of 60 nM.
  • HY-10519
    BMS-345541
    		Inhibitor 99.57%
    BMS-345541 is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM).
  • HY-10518
    BMS-345541 hydrochloride
    		Inhibitor 99.71%
    BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM).
  • HY-13060
    ACHP Hydrochloride
    		Inhibitor 99.54%
    ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.
  • HY-122881
    HOIPIN-1
    		Inhibitor
    HOIPIN-1 (JTP-0819958) is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM.
  • HY-13019
    BI605906
    		Inhibitor 99.70%
    BI605906 is a novel IKKβ inhibitor with an IC50 value of 380 nM when assayed at 0.1 mM ATP.
  • HY-13802
    SC-514
    		Inhibitor 99.88%
    SC-514 is a selective IKK-2 inhibitor (IC50=11.2 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.
  • HY-114454
    INH14
    		Inhibitor ≥98.0%
    INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively.
  • HY-19362
    AZD3264
    		Inhibitor 99.67%
    AZD3264 is a selective IkB-kinase IKK2 inhibitor.
  • HY-105661
    IMD-0560
    		Inhibitor 99.67%
    IMD-0560 is a novel IκB kinase β inhibitor.
  • HY-B0788A
    LY2409881 trihydrochloride
    		Inhibitor 98.92%
    LY2409881 trihydrochloride is a selective IκB kinase β (IKK2) inhibitor with an IC50 of 30 nM.
  • HY-13687A
    IKK 16 hydrochloride
    		Inhibitor ≥98.0%
    IKK 16 hydrochloride is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively.
  • HY-14682
    GSK319347A
    		Inhibitor 99.40%
    GSK319347A is a dual inhibitor of TBK1 and IKKε with IC50s of 93 nM and 469 nM, respectively.
  • HY-N5063
    Plantainoside D
    		Inhibitor 98.35%
    Plantainoside D shows ACE inhibitory activity with IC50 2.17 mM.
  • HY-135366
    HPN-01
    		Inhibitor 98.40%
    HPN-01 is a potent and selective IKK inhibitor, with pIC50 values of 6.4, 7.0 and <4.8 for IKK-α, IKK-β and IKK-ε, respectively.
  • HY-50948
    Bay 65-1942 hydrochloride
    		Inhibitor 99.22%
    Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor.