20554-84-1
20554-84-1
Chemical Structure
Parthenolide
Synonym(s): (-)-Parthenolide
- CAS No.: 20554-84-1
- Formula:C15H20O3
- Molecular Weight:248.32
IUPAC Name: (3aS,9aR,10aR,10bS,E)-6,9a-dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-one
InChIKey: KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES: C/C1=C\CC[C@@](C)(O2)[C@H]2[C@@H](OC(C3=C)=O)[C@H]3CC1
Biological Activity: Parthenolide is a sesquiterpene lactone found in the medicinal herb Feverfew. Parthenolide exhibits anti-inflammatory activity by inhibiting NF-κB activation; also inhibits HDAC1 protein without affecting other class I/II HDACs.
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Parthenolide | 99.91% | Parthenolide is a sesquiterpene lactone found in the medicinal herb Feverfew. Parthenolide exhibits anti-inflammatory activity by inhibiting NF-κB activation; also inhibits HDAC1 protein without affecting other class I/II HDACs. | ||||||||||||||||||||
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Parthenolide (Standard) | 99.93% | Parthenolide (Standard) is the analytical standard of Parthenolide. This product is intended for research and analytical applications. Parthenolide is a sesquiterpene lactone found in the medicinal herb Feverfew. Parthenolide exhibits anti-inflammatory activity by inhibiting NF-κB activation; also inhibits HDAC1 protein without affecting other class I/II HDACs. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.82
HY-17771414-Acetoxy parthenolide -
Similarity Score 0.79
HY-N1772811βh,13-Dihydroparthenolide -
Similarity Score 0.77
HY-N3378Lipiferolide -
Similarity Score 0.73
HY-N0847Micheliolide -
Similarity Score 0.72
HY-N17729Michelenolide -
Similarity Score 0.71
HY-N1326Santamarine -
Similarity Score 0.70
HY-N0036Costunolide -
Similarity Score 0.69
HY-N1344410β-Hydroxycadina-4,11(13)-dien-12,8β-olide -
Similarity Score 0.69
HY-N1355Reynosin -
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