Lipiferolide
Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 41059-80-7
- Formula: C17H22O5
- Molecular Weight:306.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
7.3 μM
Compound: 13
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Cytotoxicity against human A549 cells after 24 hrs by MTS assay
Cytotoxicity against human A549 cells after 24 hrs by MTS assay
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[PMID: 30289713] |
| MCF7 | IC50 |
1.5 μM
Compound: 13
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Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
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[PMID: 30289713] |
Chemical Information
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CAS No. 41059-80-7
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Molecular Weight 306.35
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Formula C17H22O5
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SMILES
C[C@]12[C@](O2)([H])[C@]3([H])[C@@](C(C(O3)=O)=C)([H])[C@@H](C/C(C)=C\CC1)OC(C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Graziose R, et al. Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. J Ethnopharmacol. 2011 Jan 7;133(1):26-30. [Content Brief]
[2]. Moon MK, et al. Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera. Arch Pharm Res. 2007 Mar;30(3):299-302. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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