41059-80-7
41059-80-7
Chemical Structure
Lipiferolide
- CAS No.: 41059-80-7
- Formula:C17H22O5
- Molecular Weight:306.35
IUPAC Name: (1aR,7R,7aR,10aS,10bS,Z)-1a,5-dimethyl-8-methylene-9-oxo-1a,2,3,6,7,7a,8,9,10a,10b-decahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-7-yl acetate
InChIKey: ODYJJNFWFYUXSS-UMCWRFCTSA-N
SMILES: C[C@]12[C@](O2)([H])[C@]3([H])[C@@](C(C(O3)=O)=C)([H])[C@@H](C/C(C)=C\CC1)OC(C)=O
Biological Activity: Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity[1][2].
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Lipiferolide | Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity. | |||||||||||||||||||||
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References
- [1]. Graziose R, et al. Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. J Ethnopharmacol. 2011 Jan 7;133(1):26-30. [Content Brief]
- [2]. Moon MK, et al. Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera. Arch Pharm Res. 2007 Mar;30(3):299-302. [Content Brief]
Keywords
