547757-23-3
547757-23-3
Chemical Structure
BMS-345541 hydrochloride
- CAS No.: 547757-23-3
- Formula:C14H18ClN5
- Molecular Weight:291.78
IUPAC Name: N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine hydrochloride
InChIKey: MIDKPVLYXNLFGZ-UHFFFAOYSA-N
SMILES: CC1=CN=C2C(NCCN)=NC3=CC=C(C=C3N21)C.Cl
Biological Activity: BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK.
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BMS-345541 hydrochloride | 99.94% | BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK. | ||||||||||||||||||||
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BMS-345541 hydrochloride (Standard) | ≥98% | BMS-345541 hydrochloride (Standard) is the analytical standard of BMS-345541 hydrochloride (HY-10518). This product is intended for research and analytical applications. BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-10519RBMS-345541 (Standard) -
Similarity Score 0.61
HY-180423IRFI-165 -
Similarity Score 0.58
HY-136392IKK-IN-3 -
Similarity Score 0.55
HY-W355129MeIQx -
Similarity Score 0.55
HY-W779191MeIQx-13C -
Similarity Score 0.54
HY-10568TC-E 5005 -
Similarity Score 0.54
HY-D0166ANeutral Red (IND) -
Similarity Score 0.54
HY-114723NPD9948 -
Similarity Score 0.53
HY-W3504477,8-DimeIQX -
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