9051-97-2
Chemical Structure
β-1,3-Glucan
Synonym(s): β Glucan
- CAS No.: 9051-97-2
- Formula:N/A
- Molecular Weight:N/A
SMILES: [beta Glucan]
Biological Activity: β-1,3-Glucan (β Glucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to Vibrio harveyi infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors[1][2][3][4][5][6][7][8].
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β-1,3-Glucan | 98.18% | β-1,3-Glucan (β Glucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to Vibrio harveyi infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors. | ||||||||||||||||||||
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- [1]. Wakshull E, et al. PGG-glucan, a soluble beta-(1,3)-glucan, enhances the oxidative burst response, microbicidal activity, and activates an NF-kappa B-like factor in human PMN: evidence for a glycosphingolipid beta-(1,3)-glucan receptor. Immunopharmacology. 1999 Feb;41(2):89-107. [Content Brief]
- [2]. Ai Q, et al. Effects of dietary beta-1, 3 glucan on innate immune response of large yellow croaker, Pseudosciaena crocea. Fish Shellfish Immunol. 2007 Apr;22(4):394-402. [Content Brief]
- [3]. Son H J, et al. Effects of β-glucan on proliferation and migration of fibroblasts. Current Applied Physics, 2005, 5(5): 468-471.
- [4]. Suzuki I, et al. Immunomodulation by orally administered β-glucan in mice. International journal of immunopharmacology, 1989, 11(7): 761-769.
- [5]. Sandvik A, et al. Oral and systemic administration of beta-glucan protects against lipopolysaccharide-induced shock and organ injury in rats. Clin Exp Immunol. 2007 Apr;148(1):168-77. [Content Brief]
- [6]. Bedirli A, et al. Beta-glucan attenuates inflammatory cytokine release and prevents acute lung injury in an experimental model of sepsis. Shock. 2007 Apr;27(4):397-401. [Content Brief]
- [7]. Torello CO, et al. β-1,3-Glucan given orally modulates immunomyelopoietic activity and enhances the resistance of tumour-bearing mice. Clin Exp Pharmacol Physiol. 2012 Mar;39(3):209-17. [Content Brief]
- [8]. Bakheet SA, et al. β-1,3-Glucan reverses aflatoxin B1-mediated suppression of immune responses in mice. Life Sci. 2016 May 1;152:1-13. [Content Brief]
Keywords