3110422-01-7
Chemical Structure
CDDO-biotin
- CAS No.: 3110422-01-7
- Formula:C43H61N5O5S
- Molecular Weight:760.04
InChIKey: QNEYJXIAJYKIIM-FVILFZCPSA-N
SMILES: O=C(N1)N[C@](CS2)([H])[C@@]1([H])[C@@H]2CCCCC(NCCNC([C@]34[C@](CC(C)(CC4)C)([H])[C@]5([H])[C@@](CC3)([C@]6(C([C@@]7([C@@](C(C)(C(C(C#N)=C7)=O)C)([H])CC6)C)=CC5=O)C)C)=O)=O
Biological Activity: CDDO-biotin is an IKKβ inhibitor with cancer cell inhibitory activity. CDDO-biotin directly interacts with and oxidizes Cys-179 in the activation loop of IKKβ, forming an adduct with wild-type IKKβ. CDDO-biotin can be used in the research of myeloid leukemia, osteosarcoma, multiple myeloma, lung cancer, breast cancer and pancreatic cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CDDO-biotin | 96.59% | CDDO-biotin is an IKKβ inhibitor with cancer cell inhibitory activity. CDDO-biotin directly interacts with and oxidizes Cys-179 in the activation loop of IKKβ, forming an adduct with wild-type IKKβ. CDDO-biotin can be used in the research of myeloid leukemia, osteosarcoma, multiple myeloma, lung cancer, breast cancer and pancreatic cancer. | ||||||||||||||||||||
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