Pyrogallol-phloroglucinol-6,6-bieckol

Name: Pyrogallol-phloroglucinol-6,6-bieckol
Brand: MedChemExpress
SKU: HY-N11729
Rating: 4.5 (1 reviews)

製品番号: HY-N11729 純度: 80.0%: Data Sheet SDS COA 取扱説明書
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Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Pyrogallol-phloroglucinol-6,6-bieckol 構造式

CAS 番号 : 1415504-32-3

容量	価格（税別）	在庫状況	数量
1 mg	$270	在庫あり	Estimated Time of Arrival: December 31
5 mg	$670	在庫あり	Estimated Time of Arrival: December 31
10 mg	$1080	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

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•関連スクリーニングライブラリ:

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•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia^[1].

分子量

974.74

分子式

C₄₈H₃₀O₂₃

CAS 番号

1415504-32-3

Appearance

Solid

Color

Light yellow to brown

SMILES

OC1=CC(OC2=C(C=C(C=C2O)OC3=CC(O)=CC(OC4=C(C=C(C(OC5=C(C6=C(C=C(C7=C6OC8=C(C(OC9=CC(O)=CC(O)=C9)=C(C=C8O)O)O7)O)O)C(O)=C%10)=C4OC5=C%10O)O)O)=C3)O)=CC(O)=C1

Structure Classification

Initial Source

Microorganisms

Ecklonia cava

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (102.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0259 mL	5.1296 mL	10.2591 mL
5 mM	0.2052 mL	1.0259 mL	2.0518 mL
10 mM	0.1026 mL	0.5130 mL	1.0259 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (2.56 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

純度とドキュメンテーション

純度: 80.0%

Select Batch:

データシート (271 KB) SDS (251 KB)

COA (252 KB) HNMR (334 KB) LCMS (94 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Lee JH, et al. Preparative isolation and purification of phlorotannins from Ecklonia cava using centrifugal partition chromatography by one-step. Food Chem. 2014 Sep 1;158:433-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0259 mL	5.1296 mL	10.2591 mL	25.6479 mL
	5 mM	0.2052 mL	1.0259 mL	2.0518 mL	5.1296 mL
	10 mM	0.1026 mL	0.5130 mL	1.0259 mL	2.5648 mL
	15 mM	0.0684 mL	0.3420 mL	0.6839 mL	1.7099 mL
	20 mM	0.0513 mL	0.2565 mL	0.5130 mL	1.2824 mL
	25 mM	0.0410 mL	0.2052 mL	0.4104 mL	1.0259 mL
	30 mM	0.0342 mL	0.1710 mL	0.3420 mL	0.8549 mL
	40 mM	0.0256 mL	0.1282 mL	0.2565 mL	0.6412 mL
	50 mM	0.0205 mL	0.1026 mL	0.2052 mL	0.5130 mL
	60 mM	0.0171 mL	0.0855 mL	0.1710 mL	0.4275 mL
	80 mM	0.0128 mL	0.0641 mL	0.1282 mL	0.3206 mL
	100 mM	0.0103 mL	0.0513 mL	0.1026 mL	0.2565 mL