Chlopynostat
Based on 1 Customer Validation
Chlopynostat (Compound 6c) is a HDAC1 inhibitor with a IC50 value of 67 nM. Chlopynostat reverses STAT4/p66Shc defects by inhibiting HDAC1-induced < b>Apoptosis.
For research use only. We do not sell to patients.
- Purity: 98.36%
- Formula: C22H17ClN4O2
- Molecular Weight:404.85
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Apoptosis Compound Library
HY-L003
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Cell Cycle/DNA Damage Compound Library
HY-L004
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Epigenetics Compound Library
HY-L005
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Histone Modification Research Compound Library
HY-L024
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Reprogramming Compound Library
HY-L039
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Oxygen Sensing Compound Library
HY-L045
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Anti-Breast Cancer Compound Library
HY-L074
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Anti-Pancreatic Cancer Compound Library
HY-L077
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Anti-Blood Cancer Compound Library
HY-L079
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Anti-Liver Cancer Compound Library
HY-L101
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Osteogenesis Compound Library
HY-L131
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Highly Selective Inhibitors Library
HY-L158
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Highly Selective Activators Library
HY-L159
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Cell Death Library
HY-L162
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Anti-Hematopathy Compound Library
HY-L171
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Brain Cancer Compound Library
HY-L188
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
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High-Throughput Bioactive Compound Library
HY-L205
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High-Efficiency Gene Editing Compound Library
HY-L244
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Lactylation Compound Library
HY-L249
Biological Activity
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HDAC1 67 nM (IC50) |
Chemical Information
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Appearance Solid
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Molecular Weight 404.85
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Formula C22H17ClN4O2
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Color White to off-white
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SMILES
O=C1N(CC2=CC=C(C(NC3=CC=CC=C3N)=O)C=C2)C=NC4=CC(Cl)=CC=C41
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (123.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4701 mL | 12.3503 mL | 24.7005 mL | 61.7513 mL |
| 5 mM | 0.4940 mL | 2.4701 mL | 4.9401 mL | 12.3503 mL | |
| 10 mM | 0.2470 mL | 1.2350 mL | 2.4701 mL | 6.1751 mL | |
| 15 mM | 0.1647 mL | 0.8234 mL | 1.6467 mL | 4.1168 mL | |
| 20 mM | 0.1235 mL | 0.6175 mL | 1.2350 mL | 3.0876 mL | |
| 25 mM | 0.0988 mL | 0.4940 mL | 0.9880 mL | 2.4701 mL | |
| 30 mM | 0.0823 mL | 0.4117 mL | 0.8234 mL | 2.0584 mL | |
| 40 mM | 0.0618 mL | 0.3088 mL | 0.6175 mL | 1.5438 mL | |
| 50 mM | 0.0494 mL | 0.2470 mL | 0.4940 mL | 1.2350 mL | |
| 60 mM | 0.0412 mL | 0.2058 mL | 0.4117 mL | 1.0292 mL | |
| 80 mM | 0.0309 mL | 0.1544 mL | 0.3088 mL | 0.7719 mL | |
| 100 mM | 0.0247 mL | 0.1235 mL | 0.2470 mL | 0.6175 mL |
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