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Cat. No.: HY-181919

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CD73-IN-22

CD73-IN-22 (Compound HX-6) is a non-nucleoside CD73 inhibitor with an IC₅₀ of 0.07 μM. When radiolabeled with ⁶⁸Ga, CD73-IN-22 acts as a PET radiotracer for detecting CD73 expression. When radiolabeled with ¹⁷⁷Lu, CD73-IN-22 exhibits anticancer activity against colorectal adenocarcinoma. CD73-IN-22 is applicable to research related to colon adenocarcinoma and breast cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₄₃H₄₅FN₁₂O₉
분자량:892.89

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CD73-IN-22 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

IC₅₀: 0.07 μM (CD73)^[1]

All Radionuclide-Drug Conjugates (RDCs) Isoforms :

In Vitro

CD73-IN-22 potently inhibits the enzymatic activity of CD73, with an IC₅₀ of 0.07 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

분자량 892.89
화학식 C₄₃H₄₅FN₁₂O₉
SMILES

OC(CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(C(CCC(N2N=CC3=C2C=C(N4C(C=C(C5=CC=NN5CC6=CC=C(C#N)C=C6)C=C7F)=C7N=N4)C=C3)=O)C(O)=O)CC1)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhao C, et al. Design, synthesis and preclinical evaluation of a tumor extracellular nucleotidase CD73 targeted theranostic radiotracer. Eur J Med Chem. 2026;308:118728. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

CD73-IN-22

All Radionuclide-Drug Conjugates (RDCs) Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CD73-IN-22 Related Classifications

HY-181919 Related Classifications

Bioz

Keywords

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