Smurf1-IN-5
Smurf1-IN-5 (Compound cpd-6) is an allosteric SMAD ubiquitin regulatory factor 1 (SMURF1) inhibitor. Smurf1-IN-5 leads to a reduction in the ubiquitylation of substrates such as BMPR2 (bone morphogenetic protein receptor 2) and SMAD1, enhancing the BMP (bone morphogenetic protein) signaling pathway. Smurf1-IN-5 is promising for research of pulmonary arterial hypertension (PAH).
For research use only. We do not sell to patients.
- CAS No.: 1824647-09-7
- Formula: C25H22ClFN4O3
- Molecular Weight:480.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1824647-09-7
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Molecular Weight 480.92
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Formula C25H22ClFN4O3
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SMILES
FC1=CC=CC=C1N2C(C(NC(C3=NOC(C4=CC=C(C5CC5)C=C4Cl)=C3C)=O)=C(C)N2C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Smurf1-IN-5 Related Classifications
HY-174416 Related Classifications
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