A-86929
A-86929 is a highly potent and selective dopamine D1 receptor agonist with a pKi value of 7.3. In the 6-OHDA (HY-B1081)-induced unilateral nigrostriatal lesion rat model, A-86929 significantly induces rotational behavior. It also improves motor function in the MPTP (HY-15608)-induced Parkinson's disease marmoset model. Additionally, A-86929 demonstrates potential therapeutic value in reducing cocaine-seeking behavior in rats and reversing Haloperidol (HY-14538)-induced cognitive deficits in rhesus monkeys. A-86929 can be used for research in neurological disorders.
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- CAS No.: 171961-95-8
- Formule: C18H21NO2S
- Masse moléculaire:315.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 171961-95-8
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Masse moléculaire 315.43
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Formule C18H21NO2S
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SMILES
CCCC1=CC([C@]2([H])C3=C4)=C(S1)CN[C@]2([H])CCC3=CC(O)=C4O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A-86929 Related Classifications
HY-171472 Related Classifications
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