BMS-195614 (Synonyms: BMS 614)

Cat. No.: HY-101259 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

BMS-195614 (BMS 614) is a neutral RARα-selective antagonist with a K_i of 2.5 nM.

For research use only. We do not sell to patients.

BMS-195614 Chemical Structure

CAS No. : 182135-66-6

Size	Price	Stock	Quantity
1 mg	USD 132	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Description

BMS-195614 (BMS 614) is a neutral RARα-selective antagonist with a K_i of 2.5 nM^[1].

Molecular Weight

448.51

Formula

C₂₉H₂₄N₂O₃

CAS No.

182135-66-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=C(NC(C2=CC=C3C(C)(C)CC=C(C4=CC5=CC=CC=C5N=C4)C3=C2)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 30 mg/mL (66.89 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2296 mL	11.1480 mL	22.2960 mL
5 mM	0.4459 mL	2.2296 mL	4.4592 mL
10 mM	0.2230 mL	1.1148 mL	2.2296 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.06%

Select Batch:

Data Sheet (245 KB) SDS (0 KB)

COA (252 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2296 mL	11.1480 mL	22.2960 mL	55.7401 mL
	5 mM	0.4459 mL	2.2296 mL	4.4592 mL	11.1480 mL
	10 mM	0.2230 mL	1.1148 mL	2.2296 mL	5.5740 mL
	15 mM	0.1486 mL	0.7432 mL	1.4864 mL	3.7160 mL
	20 mM	0.1115 mL	0.5574 mL	1.1148 mL	2.7870 mL
	25 mM	0.0892 mL	0.4459 mL	0.8918 mL	2.2296 mL
	30 mM	0.0743 mL	0.3716 mL	0.7432 mL	1.8580 mL
	40 mM	0.0557 mL	0.2787 mL	0.5574 mL	1.3935 mL
	50 mM	0.0446 mL	0.2230 mL	0.4459 mL	1.1148 mL
	60 mM	0.0372 mL	0.1858 mL	0.3716 mL	0.9290 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-195614182135-66-6BMS 614BMS195614BMS 195614BMS614BMS-614Inhibitorinhibitorinhibit

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