Pempidine hydrochloride
Pempidine (1,2,2,6,6-Pentamethylpiperidine) hydrochloride is an orally active ganglionic blocking agent used in the treatment of hypertension. Pempidine hydrochloride blocks the effects of intravenously administered addictive drugs and peripheral vagal nerve stimulation on blood pressure, and reduces the output of acetylcholine.
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- CAS. Nr.: 6152-95-0
- Formel: C10H22ClN
- Molecular Weight:191.74
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 6152-95-0
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Molecular Weight 191.74
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Formel C10H22ClN
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SMILES
CC1(C)CCCC(C)(C)N1C.Cl
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Synonyms
1,2,2,6,6-Pentamethylpiperidine hydrochloride
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Martin TJ, et al. Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine. J Pharmacol Exp Ther. 1990 Jul;254(1):45-51. [Content Brief]
[3]. Haikala, H., & Ahtee, L. (1988). Antagonism of the nicotine-induced changes of the striatal dopamine metabolism in mice by mecamylamine and pempidine. Naunyn-Schmiedeberg's archives of pharmacology, 338(2), 169–173. [Content Brief]
[4]. MUGGLETON, D. F., & READING, H. W. (1959). Absorption, metabolism and elimination of pempidine in the rat. British journal of pharmacology and chemotherapy, 14(2), 202–208. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)