Pempidine hydrochloride
Pempidine (1,2,2,6,6-Pentamethylpiperidine) hydrochloride is an orally active ganglionic blocking agent used in the treatment of hypertension. Pempidine hydrochloride blocks the effects of intravenously administered addictive drugs and peripheral vagal nerve stimulation on blood pressure, and reduces the output of acetylcholine.
For research use only. We do not sell to patients.
- CAS No.: 6152-95-0
- Formula: C10H22ClN
- Molecular Weight:191.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 6152-95-0
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Molecular Weight 191.74
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Formula C10H22ClN
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SMILES
CC1(C)CCCC(C)(C)N1C.Cl
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Synonyms
1,2,2,6,6-Pentamethylpiperidine hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Martin TJ, et al. Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine. J Pharmacol Exp Ther. 1990 Jul;254(1):45-51. [Content Brief]
[3]. Haikala, H., & Ahtee, L. (1988). Antagonism of the nicotine-induced changes of the striatal dopamine metabolism in mice by mecamylamine and pempidine. Naunyn-Schmiedeberg's archives of pharmacology, 338(2), 169–173. [Content Brief]
[4]. MUGGLETON, D. F., & READING, H. W. (1959). Absorption, metabolism and elimination of pempidine in the rat. British journal of pharmacology and chemotherapy, 14(2), 202–208. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pempidine hydrochloride Related Classifications
HY-B1382A Related Classifications
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