(6S)-Tetrahydrofolic acid
(6S)-Tetrahydrofolic acid ((6S)-5,6,7,8-Tetrahydrofolic acid) is the C6 stereoisomer of tetrahydrofolic acid (Tetrahydrofolic acid) (HY-14520), as well as the only naturally active coenzyme form produced after the reduction of folic acid by dihydrofolate reductase (DHFR). (6S)-Tetrahydrofolic acid is applicable for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 71963-69-4
- Formula: C19H23N7O6
- Molecular Weight:445.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
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Biological Activity
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Human Endogenous Metabolite |
(6S)-Tetrahydrofolic acid is an important reduced pteridine cofactor used for studying enzymatic one-carbon transfer reactions. It undergoes regioselective conversion to N5-formyl-(6S)-tetrahydrofolate without loss of enantiomeric purity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 71963-69-4
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Molecular Weight 445.43
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Formula C19H23N7O6
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SMILES
O=C1C2=C(NC(N)=N1)NC[C@@H](N2)CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O
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Synonyms
(6S)-5,6,7,8-Tetrahydrofolic acid
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(6S)-Tetrahydrofolic acid Related Classifications
HY-14520A Related Classifications
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- (6S)-Tetrahydrofolic acid
- 71963-69-4
- (6S)-5,6,7,8-Tetrahydrofolic acid
- Endogenous Metabolite
- enzymatic one-carbon transfer reactions
- pteridine cofactor
- tetrahydrofolic acid
- formic acid
- N5-formylation
- N5-formyl-(6S)-tetrahydrofolic acid
- oxidative cyclization
- reduction
- N-[4-[[2(S)-Amino-3-[(2,5-diamino-4(3H)-oxopyrimidin-6-yl)amino]propyl]amino]benzoyl]-L-glutamic Acid
- cancer
- Inhibitor
- inhibitor
- inhibit