Pemetrexed disodium heptahydrate (Standard)
Pemetrexed (disodium heptahydrate) (Standard) is the analytical standard of Pemetrexed (disodium heptahydrate). This product is intended for research and analytical applications. Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 357166-29-1
- Formula: C20H19N5Na2O6.7H2O
- Molecular Weight:597.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
-
HY-10820B
Pemetrexed disodium heptahydrate -
HY-10820
Pemetrexed -
HY-10820R
Pemetrexed (Standard) -
HY-10446
Pralatrexate -
HY-13664
Folinic acid calcium -
HY-17556
Folinic acid -
HY-13667
Levoleucovorin Calcium -
HY-14518
Aminopterin -
HY-10820A
Pemetrexed disodium -
HY-14521
Lometrexol -
HY-B0080
Folinic acid calcium salt pentahydrate -
HY-17383
Levomefolate calcium
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 357166-29-1
-
Molecular Weight 597.48
-
Formula C20H19N5Na2O6.7H2O
-
SMILES
O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(CCC2=CNC(N=C(N)N3)=C2C3=O)C=C1)=O.[7H2O]
-
Synonyms
LY231514 disodium heptahydrate (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Shih C, et al. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes. Cancer Res. 1997 Mar 15;57(6):1116-23. [Content Brief]
[2]. Anraku M, et al. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignantmesothelioma. J Immunol. 2010 Jul 15;185(2):956-66. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pemetrexed disodium heptahydrate (Standard) Related Classifications
HY-10820BR Related Classifications
Powered by Bioz