71963-69-4
Chemical Structure
(6S)-Tetrahydrofolic acid
Synonym(s): (6S)-5,6,7,8-Tetrahydrofolic acid
- CAS No.: 71963-69-4
- Formula:C19H23N7O6
- Molecular Weight:445.43
IUPAC Name: (4-((((S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid
InChIKey: MSTNYGQPCMXVAQ-RYUDHWBXSA-N
SMILES: O=C1C2=C(NC(N)=N1)NC[C@@H](N2)CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O
Biological Activity: (6S)-Tetrahydrofolic acid is 1000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae. (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein[1].
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(6S)-Tetrahydrofolic acid | (6S)-Tetrahydrofolic acid is 1000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae. (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein. | |||||||||||||||||||||
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Keywords
