6-Oxohexyl 2-hexyldecanoate, 80% (ELSD)
Based on 1 Customer Validation
6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) can be used in research on drug delivery, such as mRNA delivery.
For research use only. We do not sell to patients.
- Purity : 99.93%
- CAS No.: 1849616-54-1
- Formula: C22H42O3
- Molecular Weight:354.57
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Description
In Vitro
ALC-0315 is an ionizable amino lipid. ALC-0315 is a key component of LNP delivery vehicles[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1849616-54-1
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Appearance Liquid (Density: 0.902±0.06 g/cm3)
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Molecular Weight 354.57
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Formula C22H42O3
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Color Colorless to light yellow
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SMILES
O=CCCCCCOC(C(CCCCCCCC)CCCCCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (282.03 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8203 mL | 14.1016 mL | 28.2032 mL | 70.5079 mL |
| 5 mM | 0.5641 mL | 2.8203 mL | 5.6406 mL | 14.1016 mL | |
| 10 mM | 0.2820 mL | 1.4102 mL | 2.8203 mL | 7.0508 mL | |
| 15 mM | 0.1880 mL | 0.9401 mL | 1.8802 mL | 4.7005 mL | |
| 20 mM | 0.1410 mL | 0.7051 mL | 1.4102 mL | 3.5254 mL | |
| 25 mM | 0.1128 mL | 0.5641 mL | 1.1281 mL | 2.8203 mL | |
| 30 mM | 0.0940 mL | 0.4701 mL | 0.9401 mL | 2.3503 mL | |
| 40 mM | 0.0705 mL | 0.3525 mL | 0.7051 mL | 1.7627 mL | |
| 50 mM | 0.0564 mL | 0.2820 mL | 0.5641 mL | 1.4102 mL | |
| 60 mM | 0.0470 mL | 0.2350 mL | 0.4701 mL | 1.1751 mL | |
| 80 mM | 0.0353 mL | 0.1763 mL | 0.3525 mL | 0.8813 mL | |
| 100 mM | 0.0282 mL | 0.1410 mL | 0.2820 mL | 0.7051 mL |