Anti-inflammatory agent 64

Anti-inflammatory agent 64 (2 μM, 4 h) can significantly protect cells and promote cell proliferation in RAW264.7 cells stimulated by H₂O₂ (0.4 mM^[1].
Anti-inflammatory agent 64 (2 μM, 24 h) inhibits the production of NO (IC₅₀=0.9 μM) in RAW264.7 cells stimulated by LPS (1 μg/mL) and has anti-inflammatory effect^[1].
Anti-inflammatory agent 64 (0.125-2 μM, 4-24 h) significantly reduces the protein level of ROS and enhances HO-1 protein level in RAW264.7 cells stimulated by Rot (5 μM) and LPS (1 μM/mL) and has antioxidant effect^[1].
Anti-inflammatory agent 64 (0.5-2 μM, 24 h) can restrain IL–6 in dose dependent manner (IC₅₀=1.73 μM) and TNF-α (IC₅₀=1.52 μM)^[1].
Anti-inflammatory agent 64 (0.5-2 μM) can inhibit the expresstion of iNOS protein^[1].
Anti-inflammatory agent 64 (0.5-2 μM) inhibits the avtivition of NF-κB pathway by inhibiting the degradation and phosphorylation of IκBα in RAW264.7 cells stimulated by LPS (1 μg/mL)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.