6-MOMIPP
6-MOMIPP is a brain-penetrant microtubule disruptor that targets the colchicine site on β-tubulin. 6-MOMIPP can induce mitotic arrest and cell apoptosis. 6-MOMIPP has broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines. 6-MOMIPP can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 1961272-45-6
- Formula: C18H16N2O2
- Molecular Weight:292.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| U-251 | GI50 |
0.09 μM
Compound: 9b
|
Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B colorimetric assay
Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B colorimetric assay
|
[PMID: 27343855] |
Chemical Information
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CAS No. 1961272-45-6
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Molecular Weight 292.33
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Formula C18H16N2O2
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SMILES
O=C(C1=CC=NC=C1)/C=C/C2=C(C)NC3=C2C=CC(OC)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)