1. Apoptosis
  2. Apoptosis
  3. 6-Dehydrogingerdione

6-Dehydrogingerdione 

Cat. No.: HY-N7152
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6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5.

For research use only. We do not sell to patients.

6-Dehydrogingerdione Chemical Structure

6-Dehydrogingerdione Chemical Structure

CAS No. : 76060-35-0

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Description

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1].

In Vitro

6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1].
6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1].
6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Hep G2 cells.
Concentration: 0, 50, 100 μM.
Incubation Time: 24 h.
Result: Induced Apoptosis in Hep G2 Cells.
Molecular Weight

290.35

Formula

C₁₇H₂₂O₄

CAS No.
SMILES

CCCCCC(CC(/C=C/C1=CC=C(O)C(OC)=C1)=O)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

6-DehydrogingerdioneApoptosis6-dehydrogingerdioneDR5reactiveoxygenspeciesInhibitorinhibitorinhibit

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6-Dehydrogingerdione
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HY-N7152
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